Serum kinetics of soluble triggering receptor expressed on myeloid cells-1 differs in relation to the type of arthroplasty.

Abstract

CONTEXT:

Soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) participates in the inflammatory process.

PURPOSE:

To describe changes of sTREM-1 in the serum after hemiarthroplasty (HA) and total hip arthroplasty (THA).

METHODS:

Serial blood samples were drawn from 122 patients with hip fracture. Interleukin-6 (IL-6), sTREM-1, and C-reactive protein (CRP) were measured.

RESULTS:

IL-6 and CRP were similarly increased after both HA and THA. sTREM-1 was increased early in HA and late after THA. The only parameter that was higher among patients who developed systemic inflammatory response syndrome was IL-6.

CONCLUSIONS:

Kinetics of sTREM-1 differs among patients undergoing HA of the hip and those undergoing THA.

• Authors: Ioannis Chatziantoniou, Evangelos J Giamarellos-Bourboulis, George Diakos, Stergios N Lallos, Thomas Tsaganos, Dimitrios S Korres, Nicolas E Efstathopoulos
• Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals (Biomarkers) Vol. 16 Issue 7 Pg. 600-4 (Nov 2011) ISSN: 1366-5804 [Electronic] England
• PMID: 21942576 (Publication Type: Journal Article)

Chemical References

• Interleukin-6
• Membrane Glycoproteins
• Receptors, Immunologic
• TREM1 protein, human
• Triggering Receptor Expressed on Myeloid Cells-1
• C-Reactive Protein

Topics

• Aged
• Aged, 80 and over
• Arthroplasty (methods)
• C-Reactive Protein (analysis)
• Female
• Hip Fractures (blood, surgery)
• Humans
• Immunoenzyme Techniques
• Interleukin-6 (blood)
• Kinetics
• Male
• Membrane Glycoproteins (blood)
• Receptors, Immunologic (blood)
• Triggering Receptor Expressed on Myeloid Cells-1