Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome.

Abstract

A double-blind, placebo-controlled study of the efficacy and tolerability of 5-hydroxytryptophan (5-HTP) was conducted in 50 patients with primary fibromyalgia syndrome. All the clinical parameters studied were significantly improved by treatment with 5-HTP and only mild and transient side-effects were reported. Further controlled studies are required to define properly the value of 5-HTP in patients with primary fibromyalgia syndrome.

• Authors: I Caruso, P Sarzi Puttini, M Cazzola, V Azzolini
• Journal: The Journal of international medical research (J Int Med Res) 1990 May-Jun Vol. 18 Issue 3 Pg. 201-9 ISSN: 0300-0605 [Print] England
• PMID: 2193835 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Placebos
• 5-Hydroxytryptophan

Topics

• 5-Hydroxytryptophan (therapeutic use)
• Anxiety
• Clinical Trials as Topic
• Double-Blind Method
• Fatigue
• Fatigue Syndrome, Chronic (drug therapy, physiopathology, psychology)
• Female
• Humans
• Male
• Middle Aged
• Pain
• Placebos
• Sleep