Abstract |
Docetaxel is a commonly-used anti- cancer chemotherapeutic agent given its efficacy in a large variety of solid tumors. It is associated with various adverse effects one of which is nail toxicity. We report a case of severe onycholysis as a result of treatment with docetaxel in a patient who suffered from metastatic nasopharyngeal carcinoma. The case report will be followed by a discussion on the possible mechanism and preventive strategies for taxane-induced nail toxicity.
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Authors | Chi-Pan Lau, Pun Hui, Tak-Cheung Chan |
Journal | Chinese medical journal
(Chin Med J (Engl))
Vol. 124
Issue 16
Pg. 2559-60
(Aug 2011)
ISSN: 2542-5641 [Electronic] China |
PMID | 21933605
(Publication Type: Case Reports, Journal Article, Review)
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Chemical References |
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Topics |
- Adult
- Docetaxel
- Female
- Humans
- Nails
(drug effects, pathology)
- Onycholysis
(chemically induced)
- Taxoids
(adverse effects)
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