[Cytoprotective effect of ursodeoxycholic acid on the gastroduodenal zone mucous membrane at elderly patients with a combination of gallstone disease and duodenal ulcer].

Abstract

Was made a clinical-morphological study of elderly patients with a combination of cholelithiasis and duodenal ulcer. Was shown that prolonged ursoterapiya does not adversely affect the clinical course of duodenal ulcer, does not cause exacerbations of her elderly patients. These histological study of gastroesophageal and duodenobioptatov during treatment showed a positive effect of the ursodeoxycholic acid (UDCA) on the mucous membrane of the stomach and duodenum with the partial restoration of its structure, due to its cytoprotective effect.

• Authors: É Ia Selezneva, A A Il'chenko, B Z Chikunova
• Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology (Eksp Klin Gastroenterol) Issue 4 Pg. 44-7 ( 2011) ISSN: 1682-8658 [Print] Russia (Federation)
• PMID: 21916201 (Publication Type: English Abstract, Journal Article)

Chemical References

• Cholagogues and Choleretics
• Ursodeoxycholic Acid

Topics

• Aged
• Cholagogues and Choleretics (administration & dosage)
• Cytoprotection (drug effects)
• Duodenal Ulcer (complications, drug therapy, pathology)
• Female
• Gallstones (complications, drug therapy, pathology)
• Gastric Mucosa (pathology)
• Humans
• Intestinal Mucosa (pathology)
• Male
• Middle Aged
• Retrospective Studies
• Ursodeoxycholic Acid (administration & dosage)