Do older patients utilize excess health care resources after liver transplantation?

Liver transplantation is a highly effective treatment for end-stage liver disease. However, there is debate over the practice of liver transplantation in older recipients (age ≥ 60 years) given the relative shortage of donor grafts, worse post-transplantation survival, and concern that that older patients may utilize excess resources postoperatively, thus threatening the economic feasibility of the procedure.
To determine if patients ≥ 60 years of age utilize more health resources following liver transplantation compared with younger patients.
Consecutive adult patients who underwent primary liver transplantation (n = 208) at a single center were studied over a 2.5-year period. Data were collected on clinico-demographic characteristics and resource utilization. Descriptive statistics, including means, standard deviations, or frequencies were obtained for baseline variables. Patients were stratified into 2 groups: age ≥ 60 years (n = 51) and < 60 years (n = 157). The Chi-Square Test, Mantel-Haenszel Test, 2-sample test and odds ratios were calculated to ascertain associations between age and resource utilization parameters. Regression analyses were adjusted for model for end-stage liver disease score, location before surgery, diabetes mellitus, donor age, cold ischemia time, albumin, and diagnosis of hepatitis C.
Recipients ≥ 60 years of age have similar lengths of hospitalization, re-operative rates, need for consultative services and readmission rates following liver transplantation, but have longer lengths of stay in the intensive care (hazard ratio 1.97, p = 0.03).
Overall, liver transplant recipients ≥ 60 years of age utilize comparable resources following LT vs. younger recipients. Our findings have implications on cost-containment policies for liver transplantation.
AuthorsNeil Shankar, Mamoun AlBasheer, Paul Marotta, William Wall, Vivian McAlister, Natasha Chandok
JournalAnnals of hepatology (Ann Hepatol) 2011 Oct-Dec Vol. 10 Issue 4 Pg. 477-81 ISSN: 1665-2681 [Print] Mexico
PMID21911888 (Publication Type: Comparative Study, Journal Article)
  • Adult
  • Age Factors
  • Aged
  • Chi-Square Distribution
  • Critical Care (utilization)
  • Delivery of Health Care (economics, utilization)
  • Female
  • Health Resources (economics, utilization)
  • Humans
  • Length of Stay
  • Liver Transplantation (adverse effects, economics)
  • Male
  • Middle Aged
  • Odds Ratio
  • Ontario
  • Patient Readmission
  • Referral and Consultation (utilization)
  • Regression Analysis
  • Reoperation
  • Risk Assessment
  • Risk Factors
  • Time Factors
  • Treatment Outcome

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