Abstract | BACKGROUND: MATERIAL/METHODS: We retrospectively analysed the clinical and angiographic data in 228 AMI patients in whom the infarct-related artery (IRA) was successfully recanalized by primary PCI. Cardiac function was evaluated by use of echocardiography before discharge from hospital. RESULTS: The in-hospital mortality rate in the MIRI group was 13.4% (16/119), which was significantly higher than the 4.6% (5/109) mortality rate in the non-MIRI group (P=0.021). The median of peak serum CK level was remarkably lower in the suppression-type MIRI group than in the non-MIRI group. There were no significant differences in the peak serum CK or CK-MB levels between the irritation-type MIRI group and the non-MIRI group. The peak CK and CK-MB levels were significantly higher in the no-reflow-type MIRI group than in the non-MIRI group. Left ventricular ejection fraction in the no-reflow-type MIRI group was significantly lower than in the non-MIRI group; left ventricular end-diastolic volume was significantly higher than in the irritation-type MIRI subgroup; and left ventricular end-systolic volume was greater than that in non-MIRI group and suppression-type MIRI group. CONCLUSIONS: MIRI (especially the no-reflow type) may lead to acute hemodynamic disorders and increase the mortality rate. However, suppression- and irritation-type MIRI may imply the existence of surviving myocardium.
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Authors | Yi Luo, Yi-Zhi Pan, Chong Zeng, Guang-lian Li, Xiao-ming Lei, Zhen Liu, Shu-Feng Zhou |
Journal | Medical science monitor : international medical journal of experimental and clinical research
(Med Sci Monit)
Vol. 17
Issue 9
Pg. CR474-9
(Sep 2011)
ISSN: 1643-3750 [Electronic] United States |
PMID | 21873942
(Publication Type: Journal Article)
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Chemical References |
- Creatine Kinase
- Creatine Kinase, MB Form
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Angioplasty, Balloon, Coronary
- Creatine Kinase
(blood)
- Creatine Kinase, MB Form
(blood)
- Female
- Heart Function Tests
- Humans
- Male
- Middle Aged
- Myocardial Reperfusion Injury
(blood, diagnostic imaging, enzymology, physiopathology)
- Myocardium
(enzymology, pathology)
- Ultrasonography
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