Abstract | BACKGROUND AND PURPOSE:
Ancrod, derived from Malayan pit viper venom, has been tested as ischemic stroke treatment in clinical trials with inconsistent results. We studied the actions of ancrod on fibrinolysis pathways in patient plasma samples and endothelial cell culture systems. METHODS: RESULTS: CONCLUSIONS:
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Authors | Shuo Liu, Victor J Marder, David E Levy, Shur-Jen Wang, Fan Yang, Annlia Paganini-Hill, Mark J Fisher |
Journal | Stroke
(Stroke)
Vol. 42
Issue 11
Pg. 3277-80
(Nov 2011)
ISSN: 1524-4628 [Electronic] United States |
PMID | 21868728
(Publication Type: Comparative Study, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Chemical References |
- Culture Media, Conditioned
- Fibrin
- Ancrod
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Topics |
- Ancrod
(therapeutic use)
- Cells, Cultured
- Culture Media, Conditioned
- Endothelium, Vascular
(drug effects, metabolism)
- Fibrin
(metabolism)
- Humans
- Stroke
(blood, drug therapy)
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