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Studies on the effects of topical retinoic acid on photoageing.

Abstract
Tretinoin has been previously shown in animal and clinical studies to stimulate epidermal cell production and to be effective in the treatment of solar keratoses. A double-blind, placebo-controlled study confirmed that topical tretinoin produced an overall improvement in photoaged skin and decreased solar keratoses. There is no evidence that tretinoin has an irritative effect, nor is there any evidence that the improvement in appearance is due to oedema.
AuthorsR Marks, L Lever
JournalThe British journal of dermatology (Br J Dermatol) Vol. 122 Suppl 35 Pg. 93-5 (Apr 1990) ISSN: 0007-0963 [Print] England
PMID2186792 (Publication Type: Clinical Trial, Journal Article, Review)
Chemical References
  • Tretinoin
Topics
  • Administration, Topical
  • Double-Blind Method
  • Humans
  • Randomized Controlled Trials as Topic
  • Skin Aging (drug effects)
  • Tretinoin (administration & dosage, therapeutic use)

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