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The crisis of IRIS: what every nurse should know about immune reconstitution inflammatory syndrome in patients infected with HIV.

Abstract
Most health care providers are aware that beginning combination antiretroviral therapy (ART) for patients infected with HIV has reduced morbidity of AIDS-related opportunistic infections and subsequently reduced HIV-related mortality. Effective ART leads to significantly reduced viral loads and increased CD4+ T cell counts, especially in the first few months after initiation. ART stimulates immune system reconstitution, thereby reducing the risk of exacerbation or acquisition of an opportunistic infection.
AuthorsDonna W Roberson, Deborah Bowers
JournalThe Journal of the Association of Nurses in AIDS Care : JANAC (J Assoc Nurses AIDS Care) 2011 Sep-Oct Vol. 22 Issue 5 Pg. 345-50 ISSN: 1552-6917 [Electronic] United States
PMID21867900 (Publication Type: Case Reports, Journal Article, Review)
CopyrightCopyright © 2011 Association of Nurses in AIDS Care. Published by Elsevier Inc. All rights reserved.
Topics
  • AIDS-Related Opportunistic Infections (nursing)
  • Adult
  • Antiretroviral Therapy, Highly Active
  • CD4 Lymphocyte Count
  • Diagnosis, Differential
  • Female
  • Humans
  • Immune Reconstitution Inflammatory Syndrome (nursing)
  • Nursing Process

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