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Delayed breast implant reconstruction: a 10-year prospective study.

Abstract
Studies of complications following reconstructive surgery with implants among women with breast cancer are needed. As the, to our knowledge, first prospective long-term study we evaluated the occurrence of complications following delayed breast reconstruction separately for one- and two-stage procedures. From the Danish Registry for Plastic Surgery of the Breast, which has prospectively registered data for women undergoing breast implantations since 1999, we identified 559 women without a history of radiation therapy undergoing 592 delayed breast reconstructions following breast cancer during the period 1999 to 2006; 239 one-stage procedures and 353 two-stage procedures. The postoperative course through November 2009 was evaluated by cumulative incidence adjusting for competing risks for the selected outcomes; hematoma, infection, seroma, implant rupture, severe capsular contracture (modified Baker III and IV), extrusion of the implant, asymmetry/displacement of the implant, any complication, and reoperation. These analyses were performed both overall and separately according to type of procedure (one- or two-stage). The overall 10-year risk estimates were 68.1% for any complication, 7.7% for severe capsular contracture, 32.3% for displacement/asymmetry of the implant and 38.6% for reoperation. When comparing one- and two-stage procedures, we observed significantly higher risk estimates for infection, seroma and extrusion of the implant following two-stage procedures, whereas the risk of reoperation was significantly higher following the one-stage procedure. For both procedures, the majority of reoperations were due to asymmetry or displacement of the implant. In conclusion, non-radiated one- and two-stage delayed breast implant reconstructions are associated with substantial risks of complications and reoperation which should be taken into consideration in the planning of breast reconstruction.
AuthorsGitte B Hvilsom, Lisbet R Hölmich, Marianne Steding-Jessen, Kirsten Frederiksen, Trine F Henriksen, Loren Lipworth, Joseph K McLaughlin, Jens Jørgen Elberg, Tine E Damsgaard, Søren Friis
JournalJournal of plastic, reconstructive & aesthetic surgery : JPRAS (J Plast Reconstr Aesthet Surg) Vol. 64 Issue 11 Pg. 1466-74 (Nov 2011) ISSN: 1878-0539 [Electronic] Netherlands
PMID21865106 (Publication Type: Journal Article)
CopyrightCopyright © 2011 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
Topics
  • Adult
  • Aged
  • Breast Implants
  • Breast Neoplasms (radiotherapy, surgery)
  • Denmark (epidemiology)
  • Female
  • Humans
  • Incidence
  • Mammaplasty (methods)
  • Middle Aged
  • Postoperative Complications (epidemiology, surgery)
  • Prospective Studies
  • Registries
  • Reoperation (statistics & numerical data)
  • Risk Assessment
  • Risk Factors
  • Time Factors
  • Treatment Outcome

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