[60]Fullerene-based monolayers as neuroprotective biocompatible hybrid materials.

Abstract

Here we report on the surface immobilization of redox-active [60]fullerene derivatives and the consequent neuroprotective effects toward l-glutamate induced excitotoxicity in human derived undifferentiated neuroblastoma cells.

• Authors: Davide Giust, José Luis Albasanz, Mairena Martín, Riccardo Marega, Arnaud Delforge, Davide Bonifazi
• Journal: Chemical communications (Cambridge, England) (Chem Commun (Camb)) Vol. 47 Issue 38 Pg. 10617-9 (Oct 14 2011) ISSN: 1364-548X [Electronic] England
• PMID: 21863174 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: This journal is © The Royal Society of Chemistry 2011

Chemical References

• Biocompatible Materials
• Coordination Complexes
• Fullerenes
• Neuroprotective Agents
• Glutamic Acid
• Gold
• fullerene C60

Topics

• Biocompatible Materials (chemical synthesis, chemistry, pharmacology)
• Cell Line, Tumor
• Coordination Complexes (chemical synthesis, chemistry, pharmacology)
• Fullerenes (chemistry)
• Glutamic Acid (toxicity)
• Gold (chemistry)
• Humans
• Neurons (drug effects)
• Neuroprotective Agents (chemical synthesis, chemistry, pharmacology)