Abstract | OBJECTIVE: MATERIALS AND METHODS: Institutional review board approval was obtained for a retrospective review of medical records of patients who had undergone liver transplantation at our institution between 1997 and 2008. Informed consent was not required. Demographic information, history of gadolinium-based contrast agent exposure, stage of chronic kidney disease (CKD), and evidence of NSF were recorded. RESULTS: A total of 2142 patients who had undergone liver transplantation at our institution between 1997 and 2008 were identified. Of this total, 33% (709/2142) had documented gadolinium-based contrast agent exposure peritransplantation. Patients in CKD1 and 2, CKD3, CKD4, and CKD5 comprised 50% (352/709), 28% (200/709), 8% (60/709), and 14% (97/709), respectively. Of patients in CKD5, 76% (74/97) required dialysis. Thorough review of all patients' medical records identified one biopsy-confirmed case of NSF in the 709 patients. This patient was also in CKD5 and required dialysis. CONCLUSION:
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Authors | Daniel S Chow, Simin Bahrami, Steven S Raman, Sepehr Rotchel, James W Sayre, Ronald W Busuttil, David S Lu |
Journal | AJR. American journal of roentgenology
(AJR Am J Roentgenol)
Vol. 197
Issue 3
Pg. 658-62
(Sep 2011)
ISSN: 1546-3141 [Electronic] United States |
PMID | 21862808
(Publication Type: Journal Article)
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Chemical References |
- Contrast Media
- Gadolinium
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Topics |
- Contrast Media
(adverse effects)
- Female
- Gadolinium
(adverse effects)
- Humans
- Incidence
- Kidney Function Tests
- Liver Transplantation
- Male
- Middle Aged
- Nephrogenic Fibrosing Dermopathy
(chemically induced, epidemiology)
- Retrospective Studies
- Risk Factors
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