Coverage of gingival recession defects using acellular dermal matrix allograft with or without beta-tricalcium phosphate.

Abstract

The aim of this study was to investigate the effect of beta-tricalcium phosphate (β-TCP) particles in combination with acellular dermal matrix (ADM) allograft in gingival recession. Experimental gingival recession defects were created in beagle dogs and randomly assigned to one of the following groups: ADM, ADM + β-TCP, or coronally positioned flap (CPF; control). Tissues were histologically examined at 4, 8, or 16 weeks following treatment. A greater thickness of gingiva was observed at the sites treated in both the ADM + β-TCP and ADM groups than in the CPF group. The ADM + β-TCP group showed a statistically significant increase in both new bone and cementum formations compared to the ADM group. The results suggest that the combination of β-TCP and ADM is more effective in promoting new bone and cementum formations than ADM graft alone.

• Authors: Nobuki Okubo, Takahisa Fujita, Yoshihito Ishii, Mikio Ota, Yoshihiro Shibukawa, Satoru Yamada
• Journal: Journal of biomaterials applications (J Biomater Appl) Vol. 27 Issue 5 Pg. 627-37 (Jan 2013) ISSN: 1530-8022 [Electronic] England
• PMID: 21862508 (Publication Type: Journal Article)

Chemical References

• Calcium Phosphates
• beta-tricalcium phosphate

Topics

• Acellular Dermis
• Animals
• Calcium Phosphates
• Dogs
• Gingival Recession (surgery)
• Male
• Transplantation, Homologous