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[Combined pharmacological-surgical treatment in exudative age-related macular degeneration].

AbstractPURPOSE:
The aim of this paper is to present the early phase of treating exudative age-releted macular degeneration (AMD)--coexisting witch vitreoretinal pathology--with combined pharmacological-surgical therapy.
MATERIAL AND METHODS:
Our observation is based on one clinical case of combined therapy: pars planavitrectomy (PPV) and one intravitrealranibizumab injection. Observation is being carried on larger patient group according to the treatment scheme presented In this paper.
RESULTS:
In this case described combined pharmacological-surgical therapy allowed a significant improvement in visual acuity and closure of choroidal neovascularization (CNV), leakage confirmed by fluorescein angiography (FA) and optical coherence tomography (AMD). The treatment is being continued--another ranibizumab injection according to PRONTO study reinjection criteria.
CONCLUSIONS:
The pathomechanism of exudative AMD and coexistance of vitreoretinal pathology implications confirm reasonability of combined therapy.Due to actual clinical studies: the pharmacological -surgical treatment reduces the number of required intravitreal anti-VEGF agents injections. To confirm this observation we need to perform large randomised clinical studies.
AuthorsMałgorzata Figurska, Jacek Robaszkiewicz, Agnieszka Bogdan-Bandurska
JournalKlinika oczna (Klin Oczna) Vol. 113 Issue 1-3 Pg. 56-9 ( 2011) ISSN: 0023-2157 [Print] Poland
Vernacular TitleTerapia łaczona chirurgiczno-farmakologiczna wysiekowej postaci zwyrodnienia plamki zawiazanego z wiekiem.
PMID21853953 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Angiogenesis Inhibitors
  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Ranibizumab
Topics
  • Aged
  • Angiogenesis Inhibitors (administration & dosage)
  • Antibodies, Monoclonal (administration & dosage)
  • Antibodies, Monoclonal, Humanized
  • Combined Modality Therapy
  • Exudates and Transudates
  • Female
  • Fluorescein Angiography
  • Humans
  • Intravitreal Injections
  • Macular Degeneration (drug therapy, surgery)
  • Ranibizumab
  • Treatment Outcome
  • Vitrectomy (methods)
  • Vitreous Body (surgery)

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