Double-blind trial of pirenzepine versus sucralfate in the treatment of endoscopic duodenitis.

Abstract	Thirty dyspeptic patients with endoscopic evidence of mild to moderate (nonerosive) duodenitis were randomly assigned to treatment with 50 mg of pirenzepine twice daily or 2 gm of sucralfate twice daily for four weeks. Posttreatment endoscopy revealed normalization of duodenal mucosa in half of the patients in each treatment group. The severity of dyspeptic symptoms was significantly reduced in both groups, with no significant between-group differences.
Authors	M Guslandi, V Molteni, M Dell'Oca, E Ballarin
Journal	Clinical therapeutics (Clin Ther) 1990 Jan-Feb Vol. 12 Issue 1 Pg. 26-30 ISSN: 0149-2918 [Print] United States
PMID	2183939 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References	Pirenzepine Sucralfate
Topics	Adolescent Adult Aged Confounding Factors, Epidemiologic Double-Blind Method Duodenitis (drug therapy) Duodenoscopy Female Humans Male Middle Aged Pirenzepine (therapeutic use) Randomized Controlled Trials as Topic Sucralfate (therapeutic use)

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