Development of a new hanging-type esophageal stent for preventing migration: a preliminary study in an animal model of esophagotracheal fistula.
|
| Abstract | PURPOSE: Covered, self-expandable metallic stents (SEMS) have been enthusiastically adopted for the treatment of esophagotracheal fistula, but problems with stent migration have yet to be resolved. To overcome this problem, we have developed a new hanging-type esophageal stent designed to prevent migration, and we conducted an animal study to assess the efficacy of our method. METHODS: A total of six female pigs were used in this study. The main characteristic of our stent was the presence of a string tied to the proximal edge of the stent for fixation under the skin of the neck. The first experiment was performed to confirm technical feasibility in three pigs with esophagotracheal fistula. The second experiment was performed to evaluate stent migration and esophagotracheal fistula in three pigs. RESULTS: Creation of the esophagotracheal fistula and stent placement were technically successful in all pigs. In the first experiment, esophagotracheal fistula was sealed by stent placement. In the second experiment, no stent migration was seen 11 or 12 days after stent placement. Gross findings showed no fistulas on the esophageal or tracheal wall. CONCLUSIONS:
|
|---|---|
| Authors | Masayuki Endo, Toshio Kaminou, Yasufumi Ohuchi, Kimihiko Sugiura, Shinsaku Yata, Akira Adachi, Tsuyoshi Kawai, Syohei Takasugi, Shuichi Yamamoto, Kensuke Matsumoto, Masayuki Hashimoto, Takashi Ihaya, Toshihide Ogawa |
| Journal | Cardiovascular and interventional radiology (Cardiovasc Intervent Radiol) Vol. 35 Issue 5 Pg. 1188-94 (Oct 2012) ISSN: 1432-086X [Electronic] United States |
| PMID | 21833810 (Publication Type: Journal Article) |
| Topics |
|
Join CureHunter, for free Research Interface BASIC access!
Realize the full power of the drug-disease research graph!