Abstract | OBJECTIVE: MATERIALS AND METHODS: Expression of FASN was evaluated by immunohistochemistry in 51 oral melanocytic lesions, including 38 intramucosal nevi and 13 primary oral melanomas, in 10 cutaneous nevi and in 14 melanomas. RESULTS:
Fatty acid synthase was strongly expressed only in melanomas, either of the oral mucosa or cutaneous. On the other hand, most oral and cutaneous nevi were negative, with a few oral cases showing focal and weak expression. CONCLUSION:
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Authors | B A B de Andrade, J E León, R Carlos, W Delgado-Azañero, A Mosqueda-Taylor, E Graner, O P de Almeida |
Journal | Oral diseases
(Oral Dis)
Vol. 17
Issue 8
Pg. 808-12
(Nov 2011)
ISSN: 1601-0825 [Electronic] Denmark |
PMID | 21819495
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © 2011 John Wiley & Sons A/S. |
Chemical References |
- Antibodies
- Biomarkers, Tumor
- Coloring Agents
- Fatty Acid Synthases
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Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Antibodies
- Biomarkers, Tumor
(analysis)
- Coloring Agents
- Fatty Acid Synthases
(analysis)
- Female
- Humans
- Immunohistochemistry
- Male
- Melanocytes
(enzymology)
- Melanoma
(enzymology)
- Middle Aged
- Mouth Mucosa
(enzymology)
- Mouth Neoplasms
(enzymology)
- Nevus
(enzymology)
- Nevus, Intradermal
(enzymology)
- Nevus, Pigmented
(enzymology)
- Skin Neoplasms
(enzymology)
- Young Adult
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