[Stereotactic proton irradiation of cerebral arteriovenous malformations in patients with onset of disease in childhood].

Abstract

The report discusses the results of proton stereotactic irradiation in 27 children, aged 6-15 (mean--12.5 yrs.), and 21 adults, aged 16-47 (mean--23 yrs.), with arteriovenous malformations (AVM) in the brain. The AVM volume ranged 0.2-37.7 cu cm; absorbed dosage at dose field maximum--40-80 Gy. Complete AVM obliteration was attained in 17 (35%) (mean AVM volume--3.1 cu cm); 50% decrease and more--12 (25%)(mean AVM volume--7 cu cm). When AVM volume was cut down to less than 50% (9) (19%) (mean AVM volume--9.2 cu cm) and 10 (21%) (mean AVM volume--19.6 cu cm), no effect was reported.

• Authors: S V Gerasimov, V M Vinogradov, Iu A Garmashov, R A Shalek
• Journal: Voprosy onkologii (Vopr Onkol) Vol. 57 Issue 2 Pg. 236-40 ( 2011) ISSN: 0507-3758 [Print] Russia (Federation)
• PMID: 21809672 (Publication Type: Journal Article)

Chemical References

• Protons

Topics

• Adolescent
• Adult
• Age of Onset
• Carotid Arteries (diagnostic imaging)
• Cerebral Angiography
• Child
• Female
• Humans
• Intracranial Arteriovenous Malformations (diagnostic imaging, pathology, surgery)
• Male
• Middle Aged
• Proton Therapy
• Radiosurgery (methods)
• Radiotherapy Dosage
• Treatment Outcome
• Young Adult