Pathologic evaluation of damage to bronchial artery, bronchial wall, and pulmonary parenchyma after bronchial artery embolization with N-butyl cyanoacrylate for massive hemoptysis.

Abstract

Histologic evidence of safety after bronchial arterial embolization (BAE) with N-butyl cyanoacrylate (NBCA) should be assured. The present report describes a 78-year-old man with massive hemoptysis from lung cancer who underwent surgical lobectomy 23 days after hemostasis had been achieved via BAE with NBCA. Pathologic examination revealed that NBCA filled the lumen of bronchial branch arteries 143-1,094 μm in diameter from the lobar bronchus to subsegmental bronchus but was not seen in the lumen of the pulmonary artery or pulmonary vein. NBCA induced occlusion of bronchial branch arteries but no necrosis of the bronchial wall or pulmonary parenchyma.

• Authors: Akira Ikoma, Nobuyuki Kawai, Morio Sato, Takami Tanaka, Tetsuo Sonomura, Shinya Sahara, Kouhei Nakata, Isao Takasaka, Hiroki Minamiguchi, Motoki Nakai, Ichiro Mori
• Journal: Journal of vascular and interventional radiology : JVIR (J Vasc Interv Radiol) Vol. 22 Issue 8 Pg. 1212-5 (Aug 2011) ISSN: 1535-7732 [Electronic] United States
• PMID: 21801997 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2011 SIR. Published by Elsevier Inc. All rights reserved.

Chemical References

• Ethiodized Oil
• Enbucrilate

Topics

• Aged
• Bronchi (injuries)
• Bronchial Arteries (injuries)
• Embolization, Therapeutic (adverse effects)
• Enbucrilate (administration & dosage, adverse effects)
• Ethiodized Oil (administration & dosage)
• Hemoptysis (etiology, therapy)
• Humans
• Lung Injury (etiology)
• Lung Neoplasms (complications)
• Male