Abstract | OBJECTIVE: METHOD: RESULTS: Data were analyzed for the 56 participants randomized to 17-OHPC and 56 randomized to placebo. Delivery rates within 48 h were 11/54 (20.4%) versus 15/56 (26.8%) RR 0.76 (95% CI 0.38-1.51) and within 7 days were 13/52 (25.0%) versus 19/54 (35.2%) RR 0.71 (95% CI 0.39-1.29) for 17-OHPC and placebo groups, respectively, and were similar. Recruitment to delivery interval, gestation at delivery, delivery rate before 34 weeks' and 37 weeks' gestation, and neonatal outcomes were also similar. CONCLUSION:
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Authors | Peng Chiong Tan, Anthonia Siaw Jia King, Narayanan Vallikkannu, Siti Zawiah Omar |
Journal | Archives of gynecology and obstetrics
(Arch Gynecol Obstet)
Vol. 285
Issue 3
Pg. 585-90
(Mar 2012)
ISSN: 1432-0711 [Electronic] Germany |
PMID | 21796421
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Adrenal Cortex Hormones
- Hydroxyprogesterones
- Progestins
- Tocolytic Agents
- 17 alpha-Hydroxyprogesterone Caproate
- Nifedipine
|
Topics |
- 17 alpha-Hydroxyprogesterone Caproate
- Adrenal Cortex Hormones
(therapeutic use)
- Adult
- Double-Blind Method
- Drug Therapy, Combination
- Female
- Humans
- Hydroxyprogesterones
(administration & dosage, adverse effects)
- Infant, Newborn
- Nifedipine
(therapeutic use)
- Obstetric Labor, Premature
(drug therapy)
- Pregnancy
- Pregnancy Outcome
- Progestins
(administration & dosage, adverse effects)
- Tocolytic Agents
(therapeutic use)
- Treatment Outcome
- Young Adult
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