[D,L-kavain in comparison with oxazepam in anxiety disorders. A double-blind study of clinical effectiveness].

Abstract

In a placebo-controlled double blind clinical trial, 38 out-patients with anxiety associated with neurotic or psychosomatic disturbances were treated with D,L-Kavain (Neuronika) or Oxazepam. The anxiolytic effectiveness of the two preparations was judged by means of the Anxiety Status Inventory (ASI) and the Self-Rating Anxiety Scale (SAS) of Zung. The substances proved to be equivalent in the nature and potency of anxiolytic action. No adverse drug reactions occurred.

• Authors: D Lindenberg, H Pitule-Schödel
• Journal: Fortschritte der Medizin (Fortschr Med) Vol. 108 Issue 2 Pg. 49-50, 53-4 (Jan 20 1990) ISSN: 0015-8178 [Print] Germany
• Vernacular Title: D,L-Kavain im Vergleich zu Oxazepam bei Angstzuständen. Doppelblindstudie zur Klinischen Wirksamkeit.
• PMID: 2179082 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Plant Extracts
• Pyrans
• Pyrones
• kavain

Topics

• Adult
• Anxiety Disorders (drug therapy)
• Double-Blind Method
• Female
• Humans
• Male
• Middle Aged
• Neurotic Disorders (drug therapy)
• Plant Extracts (therapeutic use)
• Psychophysiologic Disorders (drug therapy)
• Pyrans (therapeutic use)
• Pyrones (therapeutic use)
• Randomized Controlled Trials as Topic