Abstract | BACKGROUND: OBJECTIVE: The aim of this study was to determine the effective dose of steroids in TFESI for pain reduction in patients with lumbosacral radiculopathy. STUDY DESIGN: A randomized, double blind, controlled trial. SETTING: METHODS: A total of 160 participants received 2 epidural injections of either 5 mg, 10 mg, 20 mg, or 40 mg of triamcinolone in one week intervals via TFESI. The degree of participant satisfaction and verbal numerical rating scale (VNRS) were assessed at pretreatment, one week, and 2 weeks after the first TFESI. RESULTS: The number of participants experiencing pain relief was significantly less than in other groups in the 5 mg triamcinolone group at one week after the first TFESI. There were no significant differences among the groups at one week after the second TFESI. VNRS decreased in the other groups except the triamcinolone 5 mg group at one week after the first TFESI. VNRS decreased in all groups at one week after the second TFESI. LIMITATIONS: The limitations include lack of placebo control group and lack of long-term follow-up. CONCLUSIONS:
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Authors | Seong-Sik Kang, Byeong-Mun Hwang, Hee-Jeong Son, Il-Young Cheong, Sang-Jin Lee, Sang-Hyun Lee, Tae-Yoon Chung |
Journal | Pain physician
(Pain Physician)
2011 Jul-Aug
Vol. 14
Issue 4
Pg. 361-70
ISSN: 2150-1149 [Electronic] United States |
PMID | 21785479
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Adrenal Cortex Hormones
- Anti-Inflammatory Agents
- Triamcinolone
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Topics |
- Adrenal Cortex Hormones
(administration & dosage)
- Anti-Inflammatory Agents
(administration & dosage)
- Dose-Response Relationship, Drug
- Double-Blind Method
- Female
- Humans
- Injections, Epidural
(methods)
- Intervertebral Disc Displacement
(complications)
- Lumbar Vertebrae
- Male
- Middle Aged
- Pain
(drug therapy, etiology)
- Radiculopathy
- Triamcinolone
(administration & dosage)
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