Healing of experimental apical periodontitis after apicoectomy using different sealing materials on the resected root end.

Abstract	This study evaluated apical periodontal healing after root-end sealing using 4-META/MMA-TBB resin (SB), and root-end filling using reinforced zinc oxide eugenol cement (EBA) or mineral trioxide aggregate (MTA) when root canal infection persisted. Apical periodontitis was induced in mandibular premolars of beagles by contaminating the root canals with dental plaque. After 1 month, in the SB group, SB was applied to the resected surface following apicoectomy. In the EBA and MTA groups, a root-end cavity was prepared and filled with EBA or MTA. In the control group, the root-end was not filled. Fourteen weeks after surgery, histological and radiographic analyses in a beagle model were performed. The bone defect area in the SB, EBA and MTA groups was significantly smaller than that in the control group. The result indicated that root-end sealing using SB and root-end filling using EBA or MTA are significantly better than control.
Authors	Kaori Otani, Tsutomu Sugaya, Mahito Tomita, Yukiko Hasegawa, Hirofumi Miyaji, Taichi Tenkumo, Saori Tanaka, Youji Motoki, Yasuhiro Takanawa, Masamitsu Kawanami
Journal	Dental materials journal (Dent Mater J) Vol. 30 Issue 4 Pg. 485-92 ( 2011) ISSN: 1881-1361 [Electronic] Japan
PMID	21778612 (Publication Type: Comparative Study, Journal Article)
Chemical References	Aluminum Compounds Boron Compounds Calcium Compounds Dental Cements Drug Combinations Methacrylates Methylmethacrylates Oxides Resin Cements Silicates Zinc Oxide-Eugenol Cement mineral trioxide aggregate Super-bond
Topics	Aluminum Compounds (chemistry) Alveolar Process (pathology) Animals Apicoectomy (methods) Bicuspid (pathology) Boron Compounds (chemistry) Calcium Compounds (chemistry) Dental Cements (chemistry) Dental Cementum (pathology) Dental Plaque (microbiology) Dental Pulp Cavity (microbiology) Dentin (pathology) Dogs Drug Combinations Female Methacrylates (chemistry) Methylmethacrylates (chemistry) Oxides (chemistry) Periapical Periodontitis (diagnostic imaging, therapy) Periapical Tissue (pathology) Radiography Random Allocation Resin Cements (chemistry) Retrograde Obturation (methods) Root Canal Preparation (methods) Silicates (chemistry) Wound Healing (physiology) Zinc Oxide-Eugenol Cement (chemistry)

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