Abstract | PURPOSE: MATERIALS AND METHODS: We reviewed retrospectively 225 implants placed in 30 patients who had received radiotherapy as part of the oncologic treatment. Radiation doses ranged between 50 and 70 Gy. 39 implants were placed after a combined treatment of radiotherapy and chemotherapy. Data referred to tumour type and reconstruction, presence of osteoradionecrosis, region of implant installation and type of prostheses were recorded. Survival rates were calculated with cumulative Kaplan-Meier survival curves and compared between different groups with a log-rank test. RESULTS: 152 osseointegrated implants were placed in patients who presented previous reconstruction procedure. Five patients developed osteorradionecrosis as a complication of the radiotherapy treatment. Once osteoradionecrosis had healed in these patients, 41 implants were installed. The overall 5 year survival rate in irradiated patients was 92.6%. Irradiated patients had a marginally significantly higher implant loss than non-irradiated patients. (p = 0.063). The 5 year survival rate in the osteoradionecrosis group was of 48.3% and in the non- osteoradionecrosis group 92.3%, with a statistically significant difference between both groups. (p = 0.002). CONCLUSION:
Osseointegrated implants enhance oral rehabilitation in most irradiated patients, even being an acceptable option for patients who had suffered osteoradionecrosis. Totally implant supported prostheses are recommended after irradiation providing functional, stable and aesthetically satisfactory rehabilitation.
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Authors | Maria Mancha de la Plata, Luis Naval Gías, Pedro Martos Díez, Mario Muñoz-Guerra, Raul González-García, Gui-Youn Cho Lee, Sergio Castrejón-Castrejón, Francisco J Rodríguez-Campo |
Journal | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
(J Oral Maxillofac Surg)
Vol. 70
Issue 5
Pg. 1052-63
(May 2012)
ISSN: 1531-5053 [Electronic] United States |
PMID | 21778009
(Publication Type: Comparative Study, Journal Article)
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Copyright | Copyright © 2012. Published by Elsevier Inc. |
Chemical References |
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Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Bone Transplantation
(methods)
- Carcinoma, Squamous Cell
(radiotherapy)
- Chemoradiotherapy, Adjuvant
- Dental Implantation, Endosseous
(methods)
- Dental Implants
- Dental Prosthesis, Implant-Supported
(classification)
- Dental Restoration Failure
- Female
- Follow-Up Studies
- Humans
- Male
- Mandibular Diseases
(etiology)
- Middle Aged
- Mouth Neoplasms
(radiotherapy)
- Neoadjuvant Therapy
- Orthognathic Surgical Procedures
- Osseointegration
(physiology)
- Osteoradionecrosis
(etiology)
- Radiotherapy Dosage
- Plastic Surgery Procedures
(methods)
- Retrospective Studies
- Survival Analysis
- Treatment Outcome
- Young Adult
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