Chorioretinal architecture in Aicardi syndrome: an optical coherence tomography and fluorescein angiography study.

Abstract

Aicardi syndrome is a rare congenital disorder with a classic triad of infantile spasms, chorioretinal lacunae, and agenesis of the corpus callosum. We report the use of fluorescein angiography and spectral domain optical coherence tomography to examine the posterior segment structures in an 8-month-old girl with Aicardi syndrome. Most of the observed features correlated with previously published histopathological findings, but inner nuclear layer cysts have not been previously described. To our knowledge, this is the first study of the tomographic and angiographic chorioretinal features in vivo.

• Authors: Joseph N Martel, Tina Rutar, Brandon J Lujan, Alejandra de Alba Campomanes
• Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus (J AAPOS) Vol. 15 Issue 3 Pg. 308-10 (Jun 2011) ISSN: 1528-3933 [Electronic] United States
• PMID: 21777802 (Publication Type: Case Reports, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2011 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.

Topics

• Aicardi Syndrome (diagnosis)
• Choroid Diseases (diagnosis)
• Coloboma (diagnosis)
• Cysts (diagnosis)
• Female
• Fluorescein Angiography
• Humans
• Infant
• Optic Disk (abnormalities)
• Retinal Diseases (diagnosis)
• Tomography, Optical Coherence