Role of SPECT and SPECT/CT in the Surgical Treatment of Primary Hyperparathyroidism.

Primary hyperparathyroidism is the most common cause of hypercalcemia in the outpatient population. This condition is usually the result of a single hyperfunctioning parathyroid gland. Targeted parathyroidectomy guided by intraoperative parathyroid hormone monitoring (IPM) through a small cervical incision has replaced traditional bilateral neck exploration (BNE) as the initial approach in the surgical treatment of primary hyperparathyroidism at many medical centers worldwide. Preoperative sestamibi-technetium 99m scintigraphy serves as an important prerequisite for successful targeted parathyroidectomy. Single-photon emission computed tomography (SPECT) and CT fusion, however, is a recent imaging technique that provides a three-dimensional functional image with advanced contrast resolution to greatly improve preoperative localization of parathyroid tumors.
AuthorsMichele L Taubman, Melanie Goldfarb, John I Lew
JournalInternational journal of molecular imaging (Int J Mol Imaging) Vol. 2011 Pg. 141593 ( 2011) ISSN: 2090-1720 [Electronic] Egypt
PMID21776381 (Publication Type: Journal Article)

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