SH abundant body in infantile digital fibromatosis--a histochemical study on distribution of sulfhydryl groups.

Abstract

A case of infantile digital fibromatosis was studied with regard to the distribution of -SH groups and SS linkages, using N-(7-dimethylamino-4-methyl-3-coumarinyl) maleimide (DACM) stain. Tumor cells showed a strong fluorescence in the cytoplasm from the -SH stain. A brilliant -SH fluorescence was also homogenously present on the intracytoplasmic inclusions. SS reactivity was negative. Although further studies should be necessary to ascertain this finding, the DACM stain may make a simple and objective diagnostic method of infantile digital fibromatosis.

• Authors: M Kanamori, K Hashimoto, H Tanaka, M Shimizu
• Journal: The Journal of dermatology (J Dermatol) Vol. 17 Issue 9 Pg. 559-63 (Sep 1990) ISSN: 0385-2407 [Print] England
• PMID: 2177484 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Indicators and Reagents
• Maleimides
• Sulfhydryl Compounds
• Sulfhydryl Reagents
• N-(7-dimethylamino-4-methylcoumarinyl)maleimide
• Sulfur
• Ethylmaleimide

Topics

• Ethylmaleimide
• Fibroma (chemistry)
• Foot Diseases (metabolism)
• Humans
• Inclusion Bodies (chemistry)
• Indicators and Reagents
• Infant
• Male
• Maleimides
• Skin Neoplasms (chemistry)
• Sulfhydryl Compounds (analysis)
• Sulfhydryl Reagents
• Sulfur (analysis)
• Toes