[Wound healing with Iruxol. Results of a multicenter study].

Abstract

In a multicenter study, a total of 100 wounds in 94 patients were treated with Iruxol ointment over a period of 3 weeks. The ointment was applied to the wound surface once or twice daily. The target parameters, wound debridement, granulation and epithelialization were assessed qualitatively. The area of the ulcers was determined quantitatively and approximately. In wounds considered to be uncomplicated, the results were clearly better than in so-called problem wounds, in which the blood supply obviously played a considerable role in the healing process. Postoperatively the wounds shrank by only two-thirds, while the area of problem wounds, i.e. "skin ulcerations", was reduced by only about 46%. On the whole Iruxol ointment was well tolerated. However, in two out of 32 patients with leg ulcers treatment had to be terminated due to contact dermatitis.

• Authors: E Paul
• Journal: Fortschritte der Medizin (Fortschr Med) Vol. 108 Issue 35 Pg. 679-81 (Dec 10 1990) ISSN: 0015-8178 [Print] Germany
• Vernacular Title: Wundheilung unter Iruxol. Ergebnisse einer Multicenterstudie.
• PMID: 2177443 (Publication Type: Clinical Trial, English Abstract, Journal Article, Multicenter Study)

Chemical References

• Drug Combinations
• Chloramphenicol
• iruxol
• Microbial Collagenase

Topics

• Chloramphenicol (administration & dosage, therapeutic use)
• Drug Combinations
• Humans
• Leg Ulcer (drug therapy, physiopathology)
• Microbial Collagenase (administration & dosage, therapeutic use)
• Wound Healing (drug effects)
• Wounds and Injuries (drug therapy)