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The effect of bisamidines of 2,6-diaminoanthraquinone on Entamoeba histolytica infections in rats and hamsters.

Abstract
Bisamidines of 2,6-diaminoanthraquinone have demonstrated potent activity against cecal and hepatic Entamoeba histolytica infections in rats and hamsters, respectively. A number of these compounds compared favorably, in overall drug efficacy, with metronidazole and other standard agents.
AuthorsE J Burden, S G Carvajal, P F Fabio, T L Fields, Y I Lin, K C Murdock, S A Lang Jr
JournalExperientia (Experientia) Vol. 35 Issue 1 Pg. 33-5 (Jan 15 1979) ISSN: 0014-4754 [Print] Switzerland
PMID217714 (Publication Type: Journal Article)
Chemical References
  • Amidines
  • Anthraquinones
Topics
  • Amebiasis (drug therapy)
  • Amidines (therapeutic use)
  • Animals
  • Anthraquinones (therapeutic use)
  • Cricetinae
  • Dose-Response Relationship, Drug
  • Entamoeba histolytica
  • Entamoebiasis (drug therapy)
  • Female
  • Rats
  • Structure-Activity Relationship

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