HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Successful treatment of Darier disease with oral alitretinoin].

Abstract
A 18-year-old man with severe Darier disease was treated with alitretinoin 30 mg daily. In addition he used topical keratolytic agents. The duration of treatment was 52 weeks. First significant improvement was noted within one week after starting treatment. Itchiness and erythema, particularly on the head and in the chest area, decreased spontaneously after starting the treatment. From week 4 on a remarkable reduction in scaling, fissures and hyperkeratosis was observed. After 52 weeks the patient was clear of disease, except for residual symptoms on his chest. Treatment was well tolerated without any side effects.
AuthorsS E Barnstedt
JournalDer Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 63 Issue 2 Pg. 139-41 (Feb 2012) ISSN: 1432-1173 [Electronic] Germany
Vernacular TitleErfolgreiche Therapie eines Morbus Darier mit Alitretinoin.
PMID21761212 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Dermatologic Agents
  • Alitretinoin
  • Tretinoin
Topics
  • Administration, Oral
  • Alitretinoin
  • Darier Disease (diagnosis, drug therapy)
  • Dermatologic Agents (administration & dosage)
  • Humans
  • Male
  • Treatment Outcome
  • Tretinoin (administration & dosage)
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: