Non-insulinoma pancreatogenous hypoglycemia syndrome.

Abstract

We present the case of a 55 yr female who had recurrent severe hypoglycemic attacks with neuroglycopenic symptoms and altered sensorium including coma. The hypoglycemic episodes were not related to fasting. The hypoglycemia was hyperinsulinemic but all imaging modalities for insulinoma were negative. Selective arterial calcium stimulation test localized the lesion to splenic artery territory and distal pancreatectomy left to the splenic vein was done. The histopathology was consistent with nesidioblastosis and gradient guided pancreatectomy relieved the hypoglycemic episodes.

• Authors: Chander Mohan Batra, Sundeep Singh Saluja, Rajeev Bajaj, Usha Rajshekar, Vineeta Thakur, Vimal Gupta
• Journal: The Journal of the Association of Physicians of India (J Assoc Physicians India) Vol. 59 Pg. 256-8 (Apr 2011) ISSN: 0004-5772 [Print] India
• PMID: 21755766 (Publication Type: Case Reports, Journal Article)

Chemical References

• Blood Glucose
• C-Peptide
• Hypoglycemic Agents
• Insulin
• Calcium

Topics

• Blood Glucose (metabolism)
• C-Peptide (blood)
• Calcium (blood)
• Female
• Humans
• Hyperinsulinism (complications, diagnosis, surgery)
• Hypoglycemia (diagnosis, etiology, surgery)
• Hypoglycemic Agents (therapeutic use)
• Immunohistochemistry
• Injections, Intra-Arterial
• Insulin (blood)
• Insulinoma (blood, pathology)
• Middle Aged
• Pancreatectomy
• Pancreatic Neoplasms (blood, pathology)
• Splenectomy
• Syndrome
• Treatment Outcome