Abstract | OBJECTIVE: The purpose of this paper is to evaluate laparoscopic-assisted cytoreduction for primary advanced ovarian cancer: feasibility, morbidity, response to chemotherapy and survival. METHODS: All patients with presumed stage 3/4 primary ovarian cancer underwent attempted laparoscopic cytoreduction. All patients had CT evidence of omental metastasis and ascites. A five port (5-mm) transperitoneal approach was used. A bilateral salpingo-oophorectomy, supracervical hysterectomy and omentectomy were performed with the PlasmaKinetic (PK) cutting forceps. A laparoscopic 5-mm Argon-Beam Coagulator was used to coagulate tumor in the pelvis, abdominal peritoneum, intestinal mesentery, and diaphragm. RESULTS: Twenty-three cases (92%) were successfully cytoreduced laparoscopically without conversion to laparotomy. Median operative time was 2.3h and median blood loss was 340 cc. All tumors were debulked to less than 2 cm and 36% had no residual disease. Median length of stay was 1 day. Median VAS pain score was 4-discomforting. Six patients (24%) had post-operative complications, none grades 3-4. Median overall survival is 3.5 years. CONCLUSION: Laparoscopic-assisted cytoreduction for primary advanced ovarian cancer was successful, resulting in minimal morbidity, and acceptable survival.
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Authors | James Fanning, Emmanuel Yacoub, Rod Hojat |
Journal | Gynecologic oncology
(Gynecol Oncol)
Vol. 123
Issue 1
Pg. 47-9
(Oct 2011)
ISSN: 1095-6859 [Electronic] United States |
PMID | 21741079
(Publication Type: Journal Article)
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Copyright | Copyright © 2011 Elsevier Inc. All rights reserved. |
Topics |
- Adult
- Aged
- Combined Modality Therapy
- Female
- Gynecologic Surgical Procedures
(adverse effects, methods)
- Humans
- Laparoscopy
(adverse effects, methods)
- Middle Aged
- Morbidity
- Neoplasm Staging
- Ovarian Neoplasms
(drug therapy, pathology, surgery)
- Survival Rate
- Treatment Outcome
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