[Nodular pseudoangiomatous stromal hyperplasia of the breast in two adolescents].

Abstract

Nodular pseudoangiomatous stromal hyperplasia is a very rare benign breast lesion found in 0.4% of biopsies. It usually presents as a fast-growing palpable lesion in women between 30 and 40 years of age and is exceptionally rare in adolescents. Histological examination reveals a proliferation of stromal cells from connective tissue forming anastomosed empty pseudovascular spaces lined with myofibroblasts. We present the cases of two adolescents (13 and 18 years old) with fast-growing palpable breast nodules. Both underwent breast ultrasonography and core biopsy. The ultrasonographic findings of nodular pseudoangiomatous stromal hyperplasia were indistinguishable from those reported for juvenile fibroadenoma and for phyllodes tumor. Thus, histological study was required for the definitive diagnosis. Treatment depends on the size of the nodule. In our two patients, the lesion was surgically excised through tumorectomy and mastectomy.

• Authors: I Gallardo Muñoz, J L Raya Povedano, A L Santos Romero
• Journal: Radiologia (Radiologia) Vol. 54 Issue 6 Pg. 549-52 ( 2012) ISSN: 1578-178X [Electronic] Spain
• Vernacular Title: Hiperplasia estromal seudoangiomatosa nodular de mama en dos adolescentes.
• PMID: 21737108 (Publication Type: Case Reports, English Abstract, Journal Article)
• Copyright: Copyright © 2010 SERAM. Published by Elsevier Espana. All rights reserved.

Topics

• Adolescent
• Angiomatosis (pathology)
• Breast Diseases (pathology)
• Female
• Humans
• Hyperplasia (pathology)