[Treatment of severe bruxism with botulinum toxin type A].

Abstract

INTRODUCTION:

The possible usefulness of botulinum toxin type A in the treatment of bruxism has not been studied exhaustively, being limited to some isolated case reports, two short case-series and a double-blind study involving a small number or patients. This article report our long-term experience in the treatment of bruxism with botulinum toxin type A.

PATIENTS AND METHODS:

The outcome of 19 patients with severe bruxism who underwent periodical treatment with botulinum toxin A infiltrations in both temporal and masseter muscles, using initial doses of 25 IU per muscle, during a follow-up period ranging from 0.5 to 11 years, is described. Doses were adjusted in follow-up visits according the response degree.

RESULTS:

None of the patients reported side-effects. Final doses ranged from 25 to 40 IU per muscle (mean: 29.7 ± 4.9 UI), and duration of the effect from 13 to 26 weeks (mean: 16.7 ± 5.1 weeks).

CONCLUSION:

Botulinum toxin A infiltrations are a safe and useful treatment for patients with severe bruxism.

• Authors: Hortensia Alonso-Navarro, Félix J Jiménez-Jiménez, José F Plaza-Nieto, Belén Pilo-De la Fuente, Francisco Navacerrada, Margarita Arroyo-Solera, Marisol Calleja
• Journal: Revista de neurologia (Rev Neurol) Vol. 53 Issue 2 Pg. 73-6 (Jul 16 2011) ISSN: 1576-6578 [Electronic] Spain
• Vernacular Title: Tratamiento del bruxismo grave con toxina botulínica tipo A.
• PMID: 21720976 (Publication Type: English Abstract, Journal Article)

Chemical References

• Neuromuscular Agents
• Botulinum Toxins, Type A

Topics

• Adult
• Aged
• Aged, 80 and over
• Botulinum Toxins, Type A (pharmacology, therapeutic use)
• Bruxism (drug therapy)
• Female
• Humans
• Injections, Intramuscular
• Male
• Masseter Muscle (drug effects)
• Middle Aged
• Neuromuscular Agents (pharmacology, therapeutic use)
• Temporal Muscle (drug effects)
• Treatment Outcome