[Carcinogenic effect, on the liver, of an insecticide: aramite (author's transl)].

Abstract

Aramite has been administered to male rats by oral route during 56 weeks at a daily dose of 400 mg/kg. There was a decrease of the body weight and several animals died. Liver hypertrophy was observed with neoplasic proliferation of parenchymatous cells and cholangiocarcinoma.

• Authors: F Blanc, V Ngoc-Huyen, J M Warnet, J R Claude, R Truhaut
• Journal: Toxicological European research. Recherche europeenne en toxicologie (Toxicol Eur Res) Vol. 1 Issue 1 Pg. 13-21 (Jan 1978) ISSN: 0249-6402 [Print] France
• Vernacular Title: Démonstration et modalités de l'action cancérogène hépatique d'un insecticide, l'aramite, chez le rat.
• PMID: 217127 (Publication Type: Journal Article)

Chemical References

• Alkanesulfonates
• Carcinogens
• Insecticides
• Phenyl Ethers
• sulfurous acid, 2-(p-tert-butylphenoxy)-1-methylethyl 2-chloroethyl ester

Topics

• Alkanesulfonates (pharmacology)
• Animals
• Carcinogens
• Insecticides (pharmacology)
• Liver (pathology)
• Liver Neoplasms (chemically induced, pathology)
• Male
• Phenyl Ethers (pharmacology)
• Rats
• Time Factors