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[The role of congenital Enterovirus infection in the pathogenesis of suppurative and inflammatory diseases in newborn infants].

Abstract
Newborns with suppurative-inflammatory disease were found to be at high risk of intrauterine infection with Coxsackie enteroviruses from mothers with persistent enterovirus infection; in 54.9%, congenital Coxsackie virus infection was confirmed by virus antigen identification in the urine sediment cells and autopsy material. Coxsackie A viruses were identified in 68.7% of sepsis cases, 42.6% with local purulent infection foci, and in only 6.7% of practically healthy neonates. Specific features of the clinical course are analysed together with the pathohistological picture of congenital enterovirus infection associated with the vertical virus transmission from the mother having a persistent form of this infection. A suggestion is proposed that the severe course of suppurative-inflammatory conditions and the general character of neonatal bacterial infection are largely determined by the immunodeficient states which are etiologically related to congenital enterovirus infections.
AuthorsL S Lozovskaia, G V Iatsyk, N B Kasimova, M Ia Sakhatov
JournalVestnik Akademii meditsinskikh nauk SSSR (Vestn Akad Med Nauk SSSR) Issue 7 Pg. 55-8 ( 1990) ISSN: 0002-3027 [Print] Russia (Federation)
Vernacular TitleUchastie vrozhdennoĭ énterovirusnoĭ infektsii v patogeneze gnoĭno-vospalitel'nykh zabolevaniĭ u novorozhdennykh.
PMID2171237 (Publication Type: English Abstract, Journal Article)
Topics
  • Coxsackievirus Infections (congenital, etiology)
  • Enterovirus (pathogenicity)
  • Female
  • Hepatitis, Viral, Human (congenital, etiology)
  • Humans
  • Infant, Newborn
  • Meningoencephalitis (congenital, etiology)
  • Myocarditis (congenital, etiology)
  • Pregnancy
  • Pregnancy Complications, Infectious (microbiology)

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