Abstract |
Newborns with suppurative-inflammatory disease were found to be at high risk of intrauterine infection with Coxsackie enteroviruses from mothers with persistent enterovirus infection; in 54.9%, congenital Coxsackie virus infection was confirmed by virus antigen identification in the urine sediment cells and autopsy material. Coxsackie A viruses were identified in 68.7% of sepsis cases, 42.6% with local purulent infection foci, and in only 6.7% of practically healthy neonates. Specific features of the clinical course are analysed together with the pathohistological picture of congenital enterovirus infection associated with the vertical virus transmission from the mother having a persistent form of this infection. A suggestion is proposed that the severe course of suppurative-inflammatory conditions and the general character of neonatal bacterial infection are largely determined by the immunodeficient states which are etiologically related to congenital enterovirus infections.
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Authors | L S Lozovskaia, G V Iatsyk, N B Kasimova, M Ia Sakhatov |
Journal | Vestnik Akademii meditsinskikh nauk SSSR
(Vestn Akad Med Nauk SSSR)
Issue 7
Pg. 55-8
( 1990)
ISSN: 0002-3027 [Print] Russia (Federation) |
Vernacular Title | Uchastie vrozhdennoĭ énterovirusnoĭ infektsii v patogeneze gnoĭno-vospalitel'nykh zabolevaniĭ u novorozhdennykh. |
PMID | 2171237
(Publication Type: English Abstract, Journal Article)
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Topics |
- Coxsackievirus Infections
(congenital, etiology)
- Enterovirus
(pathogenicity)
- Female
- Hepatitis, Viral, Human
(congenital, etiology)
- Humans
- Infant, Newborn
- Meningoencephalitis
(congenital, etiology)
- Myocarditis
(congenital, etiology)
- Pregnancy
- Pregnancy Complications, Infectious
(microbiology)
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