HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Effects of postweaning protein malnutrition on intestinal inositol phosphatase activities in normally weaned and neonatally undernourished rats.

Abstract
Postweaning protein malnutrition imposed on normally weaned or neonatally undernourished rats fed a low-protein diet induced retardation of body and small intestinal growth. A sparing effect on intestinal growth as compared to body growth was observed during protein malnutrition. Postweaning protein malnutrition in normally weaned rats resulted in a significant elevation of specific activities of inositol triphosphatase and phytase in duodenum and jejunum without affecting the activity in ileum. On the other hand, protein malnutrition imposed on neonatally undernourished rats resulted in a significant decrease of enzyme activities in small intestinal segments. These results suggest altered activity of intestinal inositol phosphatase in postweaning protein malnutrition with the direction of effects dependent on the neonatal nutritional status.
AuthorsR K Rao, C V Ramakrishnan
JournalJournal of pediatric gastroenterology and nutrition (J Pediatr Gastroenterol Nutr) Vol. 11 Issue 1 Pg. 96-100 (Jul 1990) ISSN: 0277-2116 [Print] United States
PMID2167359 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Phosphoric Monoester Hydrolases
  • myo-inositol-1 (or 4)-monophosphatase
  • 6-Phytase
Topics
  • 6-Phytase (metabolism)
  • Animals
  • Duodenum (enzymology, growth & development, metabolism)
  • Ileum (enzymology, growth & development, metabolism)
  • Intestine, Small (enzymology, growth & development, metabolism)
  • Jejunum (enzymology, growth & development, metabolism)
  • Phosphoric Monoester Hydrolases (metabolism)
  • Protein-Energy Malnutrition (metabolism)
  • Rats
  • Rats, Inbred Strains
  • Time Factors
  • Weaning

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: