Abstract |
Postweaning protein malnutrition imposed on normally weaned or neonatally undernourished rats fed a low-protein diet induced retardation of body and small intestinal growth. A sparing effect on intestinal growth as compared to body growth was observed during protein malnutrition. Postweaning protein malnutrition in normally weaned rats resulted in a significant elevation of specific activities of inositol triphosphatase and phytase in duodenum and jejunum without affecting the activity in ileum. On the other hand, protein malnutrition imposed on neonatally undernourished rats resulted in a significant decrease of enzyme activities in small intestinal segments. These results suggest altered activity of intestinal inositol phosphatase in postweaning protein malnutrition with the direction of effects dependent on the neonatal nutritional status.
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Authors | R K Rao, C V Ramakrishnan |
Journal | Journal of pediatric gastroenterology and nutrition
(J Pediatr Gastroenterol Nutr)
Vol. 11
Issue 1
Pg. 96-100
(Jul 1990)
ISSN: 0277-2116 [Print] United States |
PMID | 2167359
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Phosphoric Monoester Hydrolases
- myo-inositol-1 (or 4)-monophosphatase
- 6-Phytase
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Topics |
- 6-Phytase
(metabolism)
- Animals
- Duodenum
(enzymology, growth & development, metabolism)
- Ileum
(enzymology, growth & development, metabolism)
- Intestine, Small
(enzymology, growth & development, metabolism)
- Jejunum
(enzymology, growth & development, metabolism)
- Phosphoric Monoester Hydrolases
(metabolism)
- Protein-Energy Malnutrition
(metabolism)
- Rats
- Rats, Inbred Strains
- Time Factors
- Weaning
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