Abstract | OBJECTIVES: METHODS: The clinical phenotype is reported from a patient database. Flumazenil-Positron Emission Topography (FMZ-PET) and Transcranial Magnetic Stimulation (TMS) were used to study GABA neurotransmission. Electrocorticography, single cell electrophysiology, and radioligand binding studies are reported from animal studies. RESULTS: CONCLUSION:
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Authors | Phillip L Pearl, Lovy Shukla, William H Theodore, Cornelis Jakobs, K Michael Gibson |
Journal | Brain & development
(Brain Dev)
Vol. 33
Issue 9
Pg. 796-805
(Oct 2011)
ISSN: 1872-7131 [Electronic] Netherlands |
PMID | 21664777
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2011 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved. |
Chemical References |
- gamma-Aminobutyric Acid
- Succinate-Semialdehyde Dehydrogenase
|
Topics |
- Animals
- Brain Diseases, Metabolic, Inborn
(complications, metabolism, physiopathology)
- Child, Preschool
- Epilepsy
(etiology, metabolism, physiopathology)
- Humans
- Male
- Mice
- Mice, Knockout
- Positron-Emission Tomography
- Succinate-Semialdehyde Dehydrogenase
(deficiency)
- gamma-Aminobutyric Acid
(metabolism)
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