Abstract | BACKGROUND: SUBJECTS AND METHODS: A retrospective review was carried out of 144 patients who underwent flow diversion surgery in our institution during the 40-year period from 1968 to 2008 and who did not have a coexisting malignant tumor at the time of surgery. RESULTS: Of these 144 patients, 137 underwent complete cyst excision and 7 underwent pancreas head resection as flow diversion surgery. The follow-up periods ranged from 1 to 345 months and from 1 to 271 months (average, 100.2 and 94.1) in patients with type I and type IV-A cysts, respectively. Regarding surgical treatment outcome, postoperative progress was good in 130 (90.3%) of the 144 patients. Fourteen patients required hospitalization for long-term postoperative complications such as cholangitis, pancreatitis, intrahepatic calculi, pancreatic calculus, and carcinogenesis during postoperative follow-up. Of these, 2 patients who underwent surgery for type IV-A cysts died because of secondary biliary cirrhosis with liver failure and advanced intrahepatic cholangiocarcinoma, respectively. CONCLUSIONS: The present study shows that flow diversion surgery for congenital choledochal cysts with PBM significantly reduces the risk of subsequent development of malignancy in the biliary tract, and it is vital to choose the appropriate operative procedure to prevent occurrence of these postoperative complications.
|
Authors | Nobuhiro Takeshita, Takehiro Ota, Masakazu Yamamoto |
Journal | Annals of surgery
(Ann Surg)
Vol. 254
Issue 6
Pg. 1050-3
(Dec 2011)
ISSN: 1528-1140 [Electronic] United States |
PMID | 21659852
(Publication Type: Journal Article)
|
Topics |
- Adolescent
- Adult
- Aged
- Bile Duct Neoplasms
(etiology, mortality)
- Bile Ducts, Extrahepatic
(abnormalities, surgery)
- Bile Ducts, Intrahepatic
- Biliopancreatic Diversion
(methods, mortality)
- Cause of Death
- Child
- Child, Preschool
- Cholangiocarcinoma
(etiology, mortality)
- Choledochal Cyst
(mortality, surgery)
- Female
- Follow-Up Studies
- Humans
- Liver Cirrhosis, Biliary
(etiology, mortality)
- Male
- Middle Aged
- Pancreatectomy
(methods)
- Pancreatic Ducts
(abnormalities, surgery)
- Postoperative Complications
(etiology, mortality)
- Retrospective Studies
- Survival Rate
- Young Adult
|