Abstract | BACKGROUND AND STUDY AIMS: PATIENTS AND METHODS: A total of 52 patients with symptomatic malignant GOO were studied in this prospective multicenter cohort study. All patients received a D-Weave Niti-S duodenal stent (Taewoong Medical, Seoul, South Korea). Patients were followed up until withdrawal of informed consent or death. RESULTS: The cause of GOO was pancreatic cancer in the majority of patients (62%). The technical and clinical success rates were 96% and 77%, respectively. The GOO Scoring System score improved significantly (P < 0.0001) when the scores before stenting were compared with the mean scores until death. Median survival was 82 days and stent patency was observed in 75% for up to 190 days, accounting for death as a competing risk. In 13 patients (25%) stent dysfunction occurred ( tumor ingrowth in 11, stent migration in two). Over time, the body mass index, the World Health Organization performance score, and the EuroQol visual analog scale revealed a not significant change (P = 0.52, P = 0.43, and P = 0.15, respectively), whereas the global health status improved significantly (P = 0.001). CONCLUSION: Placement of a new non-foreshortening nitinol enteral stent is safe and without major complications. This stent design produces significant relief of obstructive symptoms and improves quality of life in patients with incurable malignant GOO.
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Authors | J E van Hooft, M L van Montfoort, S M Jeurnink, M J Bruno, M G Dijkgraaf, P D Siersema, P Fockens |
Journal | Endoscopy
(Endoscopy)
Vol. 43
Issue 8
Pg. 671-5
(Aug 2011)
ISSN: 1438-8812 [Electronic] Germany |
PMID | 21656455
(Publication Type: Journal Article, Multicenter Study)
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Copyright | © Georg Thieme Verlag KG Stuttgart · New York. |
Chemical References |
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Topics |
- Aged
- Alloys
- Digestive System Neoplasms
(complications)
- Female
- Gastric Outlet Obstruction
(etiology, therapy)
- Humans
- Male
- Middle Aged
- Palliative Care
- Prospective Studies
- Prosthesis Failure
- Quality of Life
- Statistics, Nonparametric
- Stents
(adverse effects)
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