Abstract | BACKGROUND:
Drug therapy is recommended in conjunction with surgery in treatment of actinomycetoma. The specific prescription depends on the type of bacteria ( actinomycetoma) or fungi ( eumycetoma) causing the disease and their in vitro antimicrobial susceptibility. OBJECTIVES: To investigate the antimicrobial susceptibility among isolates of Streptomyces spp. isolated from cases of actinomycetoma in man and animals in Sudan. METHODS: Streptomyces strains (n = 18) isolated from cases of actinomycetoma were tested in vitro against 15 commonly prescribed antibacterial agents using MIC agar dilution method as per standard guidelines. RESULTS: CONCLUSIONS: Saprophytic Streptomyces spp. cause actinomycetoma in man and animal belong to separate phenotypes and have a wide range of susceptibility patterns to antimicrobial agents, which pose a lot of difficulties in selecting effective in vivo treatment for actinomycetoma.
|
Authors | Mohamed E Hamid |
Journal | Annals of clinical microbiology and antimicrobials
(Ann Clin Microbiol Antimicrob)
Vol. 10
Pg. 24
(Jun 06 2011)
ISSN: 1476-0711 [Electronic] England |
PMID | 21645380
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
|
Topics |
- Animals
- Anti-Bacterial Agents
(pharmacology)
- Equidae
(microbiology)
- Humans
- Microbial Sensitivity Tests
- Mycetoma
(drug therapy, microbiology, veterinary)
- Streptomyces
(drug effects, isolation & purification, physiology)
- Sudan
|