HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Treatment of anemia with epoetin in kidney transplant recipients.

Abstract
The aim of this study was to analyze the prevalence and efficacy of renal anemia treated with epoetin in maintenance kidney transplant recipients in Slovenia. By the end of 2009, 107 out of 537 patients (19.9%) had been treated with epoetin. A cohort of 49 patients (45.8%) were analyzed in detail: 11 patients received epoetin alpha, 18 epoetin beta, 10 darbepoetin alpha, and 10 patients received methoxy polyethylene glycol-epoetin beta. The median epoetin dose was 0.36 µg/kg body weight per week. The median serum laboratory parameters were as follows: hemoglobin 120 g/L, hematocrit 0.36, ferritin 332 ng/mL, transferrin saturation 34%, serum creatinine 145 µmol/L, serum albumin 41 g/L, intact parathyroid hormone 79 ng/L, and C-reactive protein 3 mg/L. We concluded that the prevalence of renal anemia in kidney transplant recipients treated with epoetin was approximately 20%, and laboratory parameters suggested that the treatment of renal anemia in this study cohort was optimal.
AuthorsAndrej Bren, Miha Arnol, Aljoša Kandus, Janez Varl, Manca Oblak, Jelka Lindič, Jernej Pajek, Bojan Knap, Damjan Kovač, Gregor Mlinšek, Jadranka Buturović-Ponikvar
JournalTherapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy (Ther Apher Dial) Vol. 15 Issue 3 Pg. 257-60 (Jun 2011) ISSN: 1744-9987 [Electronic] Australia
PMID21624072 (Publication Type: Comparative Study, Controlled Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
Copyright© 2011 The Authors. Therapeutic Apheresis and Dialysis © 2011 International Society for Apheresis.
Chemical References
  • Hematinics
  • Recombinant Proteins
  • epoetin beta
  • Erythropoietin
  • Darbepoetin alfa
  • Polyethylene Glycols
  • Epoetin Alfa
  • monomethoxypolyethylene glycol
Topics
  • Adult
  • Aged
  • Anemia (drug therapy, etiology)
  • Cohort Studies
  • Darbepoetin alfa
  • Epoetin Alfa
  • Erythropoietin (analogs & derivatives, chemistry, therapeutic use)
  • Female
  • Hematinics (therapeutic use)
  • Humans
  • Kidney Transplantation
  • Male
  • Middle Aged
  • Polyethylene Glycols (chemistry)
  • Prevalence
  • Recombinant Proteins
  • Slovenia
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: