Abstract | BACKGROUND: METHODS AND RESULTS:
Hyponatremia was defined as a sodium concentration <136 mmol/L at 72h after hospitalization. First, the short-term (in-hospital mortality or congestive heart failure (CHF)) and long-term prognosis ( cardiac death, re-admission for CHF) in STEMI patients was conducted. Second, the relationship between serum sodium level and plasma AVP was investigated. In hyponatremic patients the incidence of in-hospital heart failure was significantly greater (P=0.0018), long-term cardiac death was a higher trend (17.2% vs. 6.3%, P=0.19) and re-admission due to CHF was significantly more frequent (20.7% vs. 4.5%, P=0.0024). Plasma AVP level was higher in the hyponatremia group (4.5 vs. 2.7 pg/ml, P=0.003), and it had a negative correlation with serum sodium level (r=-0.28, P=0.02). CONCLUSIONS:
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Authors | Yuko Tada, Tomohiro Nakamura, Hiroshi Funayama, Yoshitaka Sugawara, Junya Ako, San-E Ishikawa, Shin-Ichi Momomura |
Journal | Circulation journal : official journal of the Japanese Circulation Society
(Circ J)
Vol. 75
Issue 8
Pg. 1927-33
( 2011)
ISSN: 1347-4820 [Electronic] Japan |
PMID | 21617327
(Publication Type: Clinical Trial, Journal Article)
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Chemical References |
- Arginine Vasopressin
- Sodium
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Topics |
- Aged
- Aged, 80 and over
- Arginine Vasopressin
(blood)
- Female
- Heart Failure
(blood, etiology, mortality)
- Humans
- Hyponatremia
(blood, complications, mortality)
- Incidence
- Male
- Middle Aged
- Myocardial Infarction
(blood, complications, mortality)
- Sodium
(blood)
- Survival Rate
- Time Factors
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