A novel biflavonyloxymethane from Pongamia pinnata and its radical quenching activity.

Abstract

The root bark of Pongamia pinnata Pierre (syn P. glabra Vent.) has afforded a new biflavonyloxymethane, pongabiflavone, along with a known furanoflavone, 3-methoxy-(7, 8, 2", 3") furanoflavone. The structure of this new compound was elucidated from extensive spectral studies, including 2D-NMR spectroscopic experiments. The antioxidant, radical quenching activity- superoxide and nitric oxide quenching activities of both pongabiflavone and previously isolated karanjabiflavone have been evaluated which can be a key to cure Psoriasis.

• Authors: Anindita Ghosh, Suvra Mandal, Avijit Banerji, Manoj Kar, Kalyan Hazra, Julie Banerji
• Journal: Natural product communications (Nat Prod Commun) Vol. 6 Issue 5 Pg. 625-6 (May 2011) ISSN: 1934-578X [Print] United States
• PMID: 21615021 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Biflavonoids
• Free Radical Scavengers
• pongabiflavone

Topics

• Biflavonoids (chemistry, isolation & purification)
• Free Radical Scavengers (isolation & purification)
• Millettia (chemistry)
• Molecular Structure
• Pongamia (chemistry)