Abstract | INTRODUCTION: The interviewer-administered chronic respiratory questionnaire (CRQ-IA) is widely used and has demonstrated excellent properties for measuring health-related quality of life (HRQL) in patients with chronic obstructive pulmonary disease ( COPD). However, the self-administered version (CRQ-SAS) in Spanish has not been validated. The aim of this trial was to evaluate the validity and the sensitivity of the Spanish version of the CRQ-SAS in patients with COPD. MATERIAL AND METHODS: We randomized 40 patients with COPD (33 treated with pulmonary rehabilitation and 7 with liquid oxygen therapy) to one of the two methods of administration of CRQ (SAS vs. IA) both before and 8 weeks after the treatment. In addition, patients completed the SF-36 questionnaire, pulmonary function tests, and six-minute walk test. RESULTS: The CRQ-SAS demonstrated good longitudinal construct validity on all domains with a range of correlations, for the change scores, between 0.46 (P=.05) and 0.71 (P=.01). Regarding sensitivity to change, we observed a minimal clinically significant change in most domains ( fatigue 0.71 [P=.02], emotional factor 0.62 [P=.04], control of the disease 0.83 [P=.06]). CONCLUSIONS: The Spanish version of CRQ-SAS is valid for evaluating HRQL in COPD patients. The correlations of the CRQ-SAS with other tools provide construct validity and show good sensitivity to change.
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Authors | Laura Vigil, M Rosa Güell, Fátima Morante, Elena López De Santamaría, Francesca Sperati, Gordon Guyatt, Holger Schünemann |
Journal | Archivos de bronconeumologia
(Arch Bronconeumol)
Vol. 47
Issue 7
Pg. 343-9
(Jul 2011)
ISSN: 1579-2129 [Electronic] Spain |
Vernacular Title | Validez y sensibilidad al cambio de la versión española autoadministrada del cuestionario de la enfermedad respiratoria crónica (CRQ-SAS). |
PMID | 21601343
(Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)
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Copyright | 2010 SEPAR. Published by Elsevier Espana. All rights reserved. |
Topics |
- Aged
- Female
- Humans
- Language
- Male
- Pulmonary Disease, Chronic Obstructive
- Quality of Life
- Reproducibility of Results
- Sensitivity and Specificity
- Surveys and Questionnaires
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