Abstract | INTRODUCTION: AREAS COVERED: A literature search of PubMed was conducted to locate articles (up to January 2011) pertaining to original preclinical and clinical research and reviews of amylin and pramlintide. Additional sources were selected from reference lists within articles obtained through the original literature search and from the internet. This article describes the known effects of endogenous amylin and the pharmacodynamics, pharmacokinetics and clinical efficacy of pramlintide. Drug-drug interactions and safety and tolerability are also reviewed. EXPERT OPINION:
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Authors | Lisa M Younk, Maia Mikeladze, Stephen N Davis |
Journal | Expert opinion on pharmacotherapy
(Expert Opin Pharmacother)
Vol. 12
Issue 9
Pg. 1439-51
(Jun 2011)
ISSN: 1744-7666 [Electronic] England |
PMID | 21564002
(Publication Type: Journal Article, Review)
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Chemical References |
- Hypoglycemic Agents
- Islet Amyloid Polypeptide
- pramlintide
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Topics |
- Diabetes Mellitus, Type 1
(drug therapy, metabolism)
- Diabetes Mellitus, Type 2
(drug therapy, metabolism)
- Drug Interactions
- Humans
- Hypoglycemic Agents
(pharmacokinetics, therapeutic use)
- Islet Amyloid Polypeptide
(pharmacokinetics, therapeutic use)
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