The association between renal function and tooth loss in Japanese community-dwelling postmenopausal women.

Abstract

OBJECTIVES:

This study examined whether low renal function is associated with the number of remaining teeth among community-dwelling elderly Japanese.

BACKGROUND DATA:

Many elderly individuals display both low renal function and tooth loss.

MATERIALS AND METHODS:

Subjects comprised 405 randomly selected women (55-74 years old). Serum cystatin C level was used to assess renal dysfunction. Multiple linear regression analysis was used to evaluate the relationship between number of remaining teeth and serum cystatin C level, with number of remaining teeth as the dependent variable. Six variables were selected as independent variables in the final model: serum cystatin C; age; mean clinical attachment level; serum cross-linked N-telopeptide of type I collagen level; body mass index and smoking habits.

RESULTS:

Multiple linear regression analysis revealed a significant relationship between number of remaining teeth and serum cystatin C level. The beta value for serum cystatin C level for the number of remaining teeth was -0.11 (p = 0.018).

CONCLUSION:

This study indicates a relationship between serum cystatin C level and number of remaining teeth, suggesting that low renal function could be associated with tooth loss.

• Authors: Akihiro Yoshihara, Kazutoshi Nakamura, Hideo Miyazaki
• Journal: Gerodontology (Gerodontology) Vol. 29 Issue 2 Pg. e363-7 (Jun 2012) ISSN: 1741-2358 [Electronic] England
• PMID: 21557761 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: © 2011 The Gerodontology Society and John Wiley & Sons A/S.

Chemical References

• Biomarkers
• Collagen Type I
• Cystatin C
• Peptides
• collagen type I trimeric cross-linked peptide
• Osteocalcin

Topics

• Age Factors
• Aged
• Biomarkers (blood)
• Body Mass Index
• Collagen Type I (blood)
• Cystatin C (blood)
• Female
• Glomerular Filtration Rate (physiology)
• Humans
• Independent Living
• Japan
• Kidney (physiology)
• Middle Aged
• Osteocalcin (blood)
• Peptides (blood)
• Periodontal Attachment Loss (complications)
• Postmenopause (physiology)
• Renal Insufficiency (blood, complications)
• Smoking
• Tooth Loss (complications)