Abstract |
We report on a 7-year-old immunocompetent boy initially presenting with right-sided frontal cephalalgia, painful ophthalmoplegia, and ptosis for 1 month. Initial cerebrospinal fluid analysis produced normal results. Magnetic resonance imaging revealed an inflammatory pseudotumor of the right cavernous sinus after intravenous gadolinium administration, indicating a rare idiopathic inflammatory disorder of the cavernous sinus, i.e., Tolosa-Hunt syndrome. Ptosis and cephalalgia resolved after steroid treatment, although right-sided ophthalmoplegia remained. Breakthrough headache, associated with signs of meningeal irritation, developed 6 weeks later. Follow-up contrast-enhanced computed tomography revealed no enhancing cavernous soft tissue mass. A further lumbar puncture disclosed central nervous system infection with Staphylococcus saprophyticus. After 6 weeks of vancomycin, the headache resolved completely, and neuroimaging produced normal results. A diagnosis of Tolosa-Hunt syndrome should be rendered cautiously, because the etiology may involve a rare but not "idiopathic" infection. Moreover, if clinical signs are not fully responsive to steroid treatment, the underlying problems should receive careful investigation.
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Authors | Chia-Hao Kang, Yi-Chuan Huang, Chun-Chung Lui, Ying-Chao Chang, Pi-Lien Hung |
Journal | Pediatric neurology
(Pediatr Neurol)
Vol. 44
Issue 6
Pg. 471-4
(Jun 2011)
ISSN: 1873-5150 [Electronic] United States |
PMID | 21555061
(Publication Type: Case Reports, Journal Article)
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Copyright | Copyright © 2011 Elsevier Inc. All rights reserved. |
Topics |
- Child
- Humans
- Male
- Meningitis, Bacterial
(diagnosis, microbiology, therapy)
- Staphylococcal Infections
(diagnosis, microbiology, therapy)
- Staphylococcus saprophyticus
- Tolosa-Hunt Syndrome
(diagnosis, microbiology, therapy)
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