Abstract | INTRODUCTION: Current therapies for endometriosis cannot completely cure the disease, and patients present with high recurrence rates. Novel medical approaches are, therefore, needed. AREAS COVERED: EXPERT OPINION: Until recently, AIs were thought to be an alternative to current medical therapies for endometriosis. However, recent findings question their real utility in clinical practice in the context of this disease. Because there is no strong evidence of their efficacy or benefit compared to other molecules in existing clinical trials, AIs need to be investigated further in well-designed studies to confirm/disprove their hypothetical impact on endometriotic lesions.
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Authors | Sébastien Colette, Jacques Donnez |
Journal | Expert opinion on investigational drugs
(Expert Opin Investig Drugs)
Vol. 20
Issue 7
Pg. 917-31
(Jul 2011)
ISSN: 1744-7658 [Electronic] England |
PMID | 21529311
(Publication Type: Journal Article, Review)
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Chemical References |
- Aromatase Inhibitors
- Aromatase
|
Topics |
- Animals
- Aromatase
(metabolism)
- Aromatase Inhibitors
(pharmacology, therapeutic use)
- Endometriosis
(drug therapy, enzymology)
- Female
- Humans
- Randomized Controlled Trials as Topic
(methods, trends)
- Signal Transduction
(drug effects, physiology)
- Treatment Outcome
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