Abstract | BACKGROUND: METHODS: The first patient was a 46-year-old woman who underwent coiling of a 6.8 × 6.8 × 7.0-mm incidentally discovered basilar apex aneurysm. Approximately 1 month after her aneurysm coiling, she developed scintillating scotoma, and an MRI of her brain revealed bilateral white matter changes with punctate enhancement. The second patient, a 56-year-old woman, developed paresthesias and gait instability 1 month after retreatment of a ruptured 12 × 8-mm basilar tip aneurysm with stent assisted coiling. MRI of the brain also revealed bilateral white matter changes with punctate enhancement as well as an area of restricted diffusion in her pons. RESULTS: Both patients underwent aneurysm coiling with PGLA coils. An extensive clinical evaluation revealed no specific etiology. The patients' symptoms and MRI abnormalities improved spontaneously over a period of weeks. CONCLUSIONS: Conclusions: After extensive evaluation for alternate causes of disease, we hypothesize that the patients' symptoms and MRI findings, which were not all within the territory supplied by the coiled vessel, were due to an overexuberant inflammatory response related to the PGLA coils. These cases highlight the importance of heightened clinical suspicion of neurologic complaints in the subacute period after aneurysm coiling. We recommend a low threshold for neuroimaging of these patients.
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Authors | Lesli E Skolarus, Joseph J Gemmete, Tiffany Braley, Lewis B Morgenstern, Aditya Pandey |
Journal | World neurosurgery
(World Neurosurg)
Vol. 74
Issue 6
Pg. 640-4
(Dec 2010)
ISSN: 1878-8769 [Electronic] United States |
PMID | 21492633
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2010 Elsevier Inc. All rights reserved. |
Chemical References |
- Polyesters
- Polymers
- Polyglycolic Acid
- Lactic Acid
- poly(lactide)
|
Topics |
- Embolization, Therapeutic
(adverse effects, instrumentation, methods)
- Encephalitis
(etiology, pathology)
- Female
- Humans
- Intracranial Aneurysm
(therapy)
- Lactic Acid
- Leukoencephalopathies
(etiology, pathology)
- Magnetic Resonance Imaging
- Middle Aged
- Polyesters
- Polyglycolic Acid
- Polymers
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